CO-CULTURE MODEL OF B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA RECAPITULATES A TRANSCRIPTION SIGNATURE OF CHEMOTHERAPY-REFRACTORY MINIMAL RESIDUAL DISEASE

Co-culture model of B-cell acute lymphoblastic leukemia recapitulates a transcription signature of chemotherapy-refractory minimal residual disease

Abstract B-cell acute lymphoblastic leukemia (ALL) is Assembly Parts (OE Style) characterized by accumulation of immature hematopoietic cells in the bone marrow, a well-established sanctuary site for leukemic cell survival during treatment.While standard of care treatment results in remission in most patients, a small population of patients will re

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Synthesis of Altissimacoumarin D and Other Prenylated Coumarins and Their Ability to Reverse the Multidrug Resistance Phenotype in Candida albicans

Azoles Solutions are the main antifungal agents employed in clinical practice to treat invasive candidiasis.Nonetheless, their efficacy is limited by fungal resistance mechanisms, mainly the overexpression of efflux pumps.Consequently, candidiasis has a worrisome death rate of 75%.One potential strategy to overcome efflux-mediated resistance is to

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Translating English Medical Terms into Indonesian: A Study of Phonological Translation and Spelling Adjustment

This study investigates phonological translation and spelling adjustment as linguistic phenomena in the translation of English medical terms into Indonesian.It aims at identifying the phonological translation and describing spelling adjustment taking place in English-Indonesian medical terms translation.Here, phonological adaptation is specifically

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